FBXL14 Antikörper (N-Term)

Produktnummer ABIN2774033

Dieser Anti-FBXL14 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von FBXL14 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für FBXL14 Antikörper (N-Term) (ABIN2774033)

Target: FBXL14 (F-Box and Leucine-Rich Repeat Protein 14 (FBXL14))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXL14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FBXL14 Antikörper

Bindungsspezifität: N-Term

Sequenz: WRDAAYHKSV WRGVEAKLHL RRANPSLFPS LQARGIRRVQ ILSLRRSLSY

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXL14. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXL14

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 418 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXL14

Target: FBXL14 (F-Box and Leucine-Rich Repeat Protein 14 (FBXL14))

Andere Bezeichnung: FBXL14

Hintergrund: FBXL14 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: Fbl14, MGC40195
Protein Interaction Partner: DICER1, HSP90AA1, COPS5, COPS6, CUL1, Snai1,
Protein Size: 418

Molekulargewicht: 46 kDa

Gen-ID: 144699

NCBI Accession: NM_152441, NP_689654

UniProt: Q8N1E6